麻豆精选

New award for research on genetic mutations offers hope for treating thrombosis

Professor Neil Morgan has been awarded a research grant to investigate the role of genetic mutations in preventing thrombosis.

Professor Neil Morgan

Professor Neil Morgan

New research will consider how genetic mutations that cause abnormal bleeding appear to protect against deep vein thrombosis (DVT). The project, funded by the as two separate awards, totalling 拢426,000 will fund a postdoctoral fellow and non-clinical PhD studentship.

DVT and Pulmonary embolism (PE) are major health problems and are collectively the most common cardiovascular cause of death globally, with an incidence of 1 in 1000 people. Understanding the role of naturally occurring mutations in patients can inform the disease processes and lead to the development of new drug targets and medications.

DVT is the formation of a blood clot (thrombus) within the deep veins, typically of the lower limbs. This thrombus may rupture and fragments can travel in the blood circulation to the lungs causing a pulmonary embolism (PE), a major medical condition with high death rates.

Current treatments for DVT act on the making of blood clots (anticoagulants) or destroying the clot (thrombolytics), but can cause increased risk of bleeding and brain bleeds with a poor patient outcome.

Professor Morgan鈥檚 research group have discovered that a new protein called Schlafen-14 is faulty in humans and causes bleeding and abnormal platelet and red blood cells, which make up a blood clot. The project will examine how mutations in Schlafen-14 may lead to stopping a blood clot and therefore may provide a new target to prevent DVT and related thrombotic disease and complications.

Professor Neil Morgan, Professor of Cardiovascular Genetics and Theme Lead for the Thrombosis and Haemostasis theme at the University 麻豆精选 has recently been elected as the new president for the . His term will be a 2-year appointment from 2026 - 2027 and is currently the new President Elect until in position.

I am delighted to be elected as the next BSHT President and feel honoured to serve the Society, at a very exciting time for this field of research.

Professor Neil Morgan

Professor Morgan said, 鈥淚 believe I am an excellent figurehead to take the BSHT society into the next era and to nurture and grow our societies鈥 mission and strategic goals. As a current trustee, I see that the BSHT is currently in an excellent position moving forward where I think we can grow the society even further. This will align with the current strategy and help to further develop the Early Career Researcher (ECR) side and interactions with other societies鈥.

Professor Morgan was elected as president for his sustained and proven international reputation as a leader in the field of thrombosis and haemostasis. He is a world leader in platelet research with a current H-index of 60 and over 130 primary peer reviewed articles in the highest impact journals. He is also the incoming Theme lead (Platelets and Megakaryocytes) for the 2026 International Society of Haemostasis and Thrombosis (ISTH) in Paris.