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Dr Saponaro is interested in characterising mechanisms of genome stability maintenance. In particular, he is interested in understanding how RNA Pol II transcription and DNA replication are coordinated, and how in context with defective transcription this can lead to increased genome instability. He develops his research combining whole genome analyses with functional studies. He characterises ...

My prime research interest is how the information encoded in chromosomes instructs building of the most complex organ, the brain, and allows an organism to perform elaborate tasks.

Professor Stankovic is a passionate advocate of translational research in the fields of DNA damage response and hematologic malignancies. For over two decades, her group has studied different ways to manipulate defective DNA damage responses in tumour cells for therapeutic benefit. A particular emphasis is given to the concept of synthetic lethality and pharmacological targeting of compensatory ...

Professor Grant Stewart is a Professor of Cancer Genetics in the Department of Cancer and Genomic Sciences.

Defective repair of DNA damage is the most frequent underlying cause of genetic instability and cancer development. Professor Stewart's research focuses on understanding how the cell detects and repairs damage to its DNA and how defects in this process contribute to the development of ...