Mr Neeraj Lal MBBS BSc PhD MRCS

Mr Neeraj Lal

Department of Applied Health Sciences
Academic Clinical Lecturer in General Surgery

Contact details

Email
n.lal.4@bham.ac.uk
Twitter
Address
University 麻豆精选
Edgbaston
Birmingham
B15 2TT
UK

Mr Neeraj Lal is an Academic Clinical Lecturer in General Surgery.  His major research interest is in the immunogenomics of colorectal cancer, with the aim of developing new immunotherapeutic strategies in this common cancer type.  He has held current and previous research funding from the National Institute of Health and Care Research, Cancer Research UK, the Medical Research Council and the Royal College of Surgeons (England).

Qualifications

  • PhD Cancer Sciences
  • MRCS (England)
  • MBBS
  • BSc Neuroscience

Biography

Neeraj completed core surgical training and then undertook his Cancer Research UK-funded PhD at the University 麻豆精选 in  Professor Willcox’s laboratory, with further supervision by Professor Gary Middleton and Professor Chris Tselepis.  This work investigated the immunogenomics of colorectal cancer, and led to multiple high impact publications that enhanced understanding of intra-tumoural immune responses. 

After completing his PhD, Neeraj was appointed as an NIHR Academic Clinical Lecturer in Professor Andrew Beggs’ group and the Academic Department of Surgery to further develop his work in the field of immunogenomics with the aim of successfully applying immunotherapeutics in colorectal cancer. 

Neeraj is currently focused on the development of and application of cancer organoid and immune cell co-culture models to identify and investigate novel targets for cancer immunotherapies. 

He is co-investigator on the ORB-AZ and Target ID studies, as well as the ROSSINI II  Randomised Clinical Trial.

Teaching

Postgraduate supervision

Neeraj is supervising multiple clinical and non-clinical PhD students. He is interested in supervising doctoral research students in the following areas:

  • Solid tumour genetics/biology
  • Molecular pathology
  • Cancer immunology and immunotherapy

Research

Research interests

Cancer immunology; cancer genetics and genomics; bioinformatics; organoid models

  • Google Scholar Profile
  • ResearchGate Profile

Other activities

Specialty Registrar in General and Colorectal Surgery

Publications

Recent publications

Article

Leung, EYL, Robbins, HL, Zaman, S, Lal, N, Morton, D, Dew, L, Williams, AP, Wallis, Y, Bell, J, Raghavan, M, Middleton, G & Beggs, AD 2024, '', British Journal of Cancer, vol. 131, no. 11, pp. 1805-1813.

Pickles, OJ, Wanigasooriya, K, Ptasinska, A, Patel, AJ, Robbins, HL, Bryer, C, Whalley, CM, Tee, L, Lal, N, Pinna, M, Elzefzafy, N, Taniere, P, Beggs, AD & Middleton, GM 2023, '', Cancer Research Communications, vol. 3, no. 8, pp. 1501-1513.

The LFD AI Consortium 2022, '', Cell Reports Medicine, vol. 3, no. 10, 100784.

Wanigasooriya, K, Sarma, D, Woods, P, O鈥檆onnor, P, Matthews, A, Aslam, M, Dando, C, Ferguson, H, Francombe, J, Lal, N, Murphy, P, Papettas, T, Ramcharan, S & Busby, K 2022, '', Annals of the Royal College of Surgeons of England.

Cragg, J, Mushtaq, F, Lal, N, Garnham, A, Hallissey, M, Graham, T & Shiralkar, U 2021, '', BJS Open, vol. 5, no. 3, zrab003.

RIFT Study Group on behalf of the West Midlands Research Collaborative & Morton, D 2020, '', The Lancet Child & Adolescent Health.

Brooks, J, Antao Mobre De Menezes, ARE, Ibrahim, M, Archer, L, Lal, N, Bagnall, C, Zeidler, SVV, Valentine, H, Spruce, R, Batis, N, Bryant, J, Hartley, M, Kaul, B, Ryan, G, Bao, R, Khattri, A, Lee, S, Ogbureke, KUE, Middleton, G, Tennant, D, Beggs, A, Deeks, J, West, CML, Cazier, J-B, Willcox, B, Seiwert, TY & Mehanna, H 2019, '', Clinical Cancer Research, vol. 25, no. 17, pp. 5315-5328. ,

Horniblow, RD, Bedford, M, Hollingworth, R, Evans, S, Sutton, E, Lal, N, Beggs, A, Iqbal, TH & Tselepis, C 2017, '', Cancer Science.

Lal, N, Willcox, C, Beggs, A, Taniere, P, Middleton, G, Tselepis, C & Willcox, B 2017, '', Journal of Pathology: Clinical Research, vol. 3, no. 3, pp. 155鈥�170.

Lal, N, White, BS, Goussous, G, Pickles, OJ, Mason, M, Beggs, AD, Taniere, P, Willcox, BE, Guinney, J & Middleton, G 2017, '', Clinical Cancer Research.

Pachnio, A, Ciaurriz, M, Begum, J, Lal, N, Zuo, J, Beggs, A & Moss, P 2016, '', PLoS pathogens, vol. 12, no. 9, e1005832.

Lal, N, Beggs, AD, Willcox, BE & Middleton, GW 2015, '', OncoImmunology, vol. 4, no. 3, e976052.

Bhangu, A, Nepogodiev, D, Lal, N & Bowley, DM 2012, '', Injury, vol. 43, no. 9, pp. 1337-1346.

Lal, N, Singh, P, Sellahewa, C & Patel, R 2012, '', International journal of surgery (London, England), vol. 10, no. 9, pp. 480-483.

Abstract

Mehanna, HM, Brooks, J, Menezes, A, Ibrahim, M, Lal, N, Archer, L, Zeidler, SV, Bao, R, Khattri, A, Valentine, H, Spruce, R, Batis, N, Bryant, J, Beggs, AD, Tennant, D, West, C, Middleton, GW, Cazier, J-B, Willcox, B & Seiwert, TY 2018, '', Journal of Clinical Oncology, vol. 36, no. 15 Suppl, pp. 6049-6049.