Professor Steve Busby FRS

School of Biosciences
Professor of Biochemistry

Contact details

Telephone
+44 (0)121 414 5439
Email
s.j.w.busby@bham.ac.uk
Address
W111, School of Biosciences
University 麻豆精选
Edgbaston
Birmingham
B15 2TT
UK

Research in Steve Busby’s lab is concerned with understanding the molecular mechanisms that control gene expression in bacteria, with particular attention to studying the regulation of transcription initiation in Escherichia coli. Much of the recent work has focussed on the expression of virulence determinants in pathogenic strains.

Qualifications

  • BA 1972 University of Cambridge, Natural Sciences 
  • DPhil 1975 University of Oxford

Teaching

Steve teaches on undergraduate courses at all levels. His biggest contributions are to a second year course on bacterial genes and genomes, and a third year course on bacterial gene regulation. He is currently the Coordinator for the School’s Taught Masters and MRes Programmes.

Other activities

Vice Chair then Chair of the Biochemical Society (2011-2016)

Head of University 麻豆精选 School of Biosciences (2012-2016)

Member of BBSRC Committee E (Fellowships)

During the past 2 years, Steve gave invited lectures at: Solihull 6th Form College (Biology Dept); University of Manchester Leaders in Science Lecture (Faculty of Life Sciences); University of Warwick (Division of Microbiology & Infection); University of Oxford (Synthetic Circuit Design MSc);Oundle School 6th Form (Evening Lecture Series); University 麻豆精选 (Biosciences Evening Lecture series); Concord College, Shrewsbury (Readers and Writers Festival); West Midlands Guild of Graduates Evening Lecture; Rutherford Appleton Laboratory (Harwell); NCBS Molecular Biology (Bangalore); ASE Annual Meeting (Birmingham); University of Salford (Health Forum); University of Marburg (Microbiology); Loyola University Medical School (Chicago); UAM Cuernavaca (Bioinformatics); Denbigh High School (Milton Keynes); NUS Mechanobiology Institute (Singapore)

During the past 24 months, Steve spoke at the following international meetings: Synthetic Biology in Action Course (EMBO Lab Heidelberg); 13th FASEB meeting on Bacterial Transcription (Vermont, USA); 77th Harden Conference on 2-component signaling in bacteria (Chesford Grange, Warwickshire); M4 Midland Microbiology Meeting (Nottingham); 7th Sunny Forum (Sun-Yat Sen University, Guangzhou); Indian Institute of Science-MCB75 Meeting (Bangalore); ASM Annual Meeting Microbe 2016 (Boston, USA); Microbiology Society Annual Meeting Marjory Stephenson Lecture (Edinburgh); BIOTEC2017 Plenary Lecture (Murcia, Spain); 14th FASEB meeting on Bacterial Transcription (Vermont, USA)

Publications

Recent publications

Article

Otoni膷ar, J, Hostnik, M, Grundner, M, Kostanj拧ek, R, Gredar, T, Garvas, M, Arsov, Z, Podlesek, Z, Gostin膷ar, C, Jak拧e, J, Busby, SJW & Butala, M 2022, '', Nucleic Acids Research, vol. 50, no. 19, e113.

Blair, JMA, Siasat, P, McNeil, HE, Colclough, A, Ricci, V, Lawler, AJ, Abdalaal, H, Buckner, MMC, Baylay, A, Busby, SJ & Piddock, LJV 2022, '', Journal of Antimicrobial Chemotherapy.

Hothersall, J, Lai, S, Zhang, N, Godfrey, R, Ruanto, P, Bischoff, S, Robinson, C, Overton, T, Busby, S & Browning, D 2022, '', Biotechnology and Bioengineering, vol. 119, no. 6, pp. 1614-1623.

Hothersall, J, Osgerby, A, Godfrey, R, Overton, T, Busby, S & Browning, D 2022, '', New Biotechnology, vol. 72, pp. 89-96.

Alhammadi, MM, Godfrey, RE, Ingram, JO, Singh, G, Bathurst, CL, Busby, SJW & Browning, DF 2022, '', Virulence, vol. 13, no. 1, pp. 1393-1406.

Abdelwahab, R, Alhammadi, MM, Hassan, EA, Ahmed, EH, Abu-faddan, NH, Daef, EA, Busby, SJW & Browning, DF 2021, '', Microorganisms, vol. 9, no. 9, 1880.

Hothersall, J, Godfrey, R, Fanitsios, C, Overton, T, Busby, S & Browning, D 2021, '', New Biotechnology, vol. 64, pp. 1-8.

Ruanto, P, Chismon, DJ, Hothersall, J, Godfrey, RE, Lee, DJ, Busby, SJW & Browning, DF 2020, '', The Biochemical journal, vol. 477, no. 15, pp. 2807-2820.

脡cija-Conesa, A, Gallego-Jara, J, Lozano Terol, G, Browning, DF, Busby, SJW, Wolfe, AJ, C谩novas D铆az, M & de Diego Puente, T 2020, '', FEMS Microbiology Letters, vol. 367, no. 20.

Abdelwahab, R, Yasir, M, Godfrey, RE, Christie, GS, Element, SJ, Saville, F, Hassan, EA, Ahmed, EH, Abu-Faddan, NH, Daef, EA, Busby, SJW & Browning, DF 2020, '', Virulence, vol. 12, no. 1, pp. 57-74.

Mej铆a-Almonte, C, Busby, SJW, Helden, JV, Arkin, AP, Stormo, GD, Eilbeck, K, Palsson, BO, Galagan, JE & Collado-Vides, J 2020, '', Nature Reviews Genetics, vol. 21, no. 11, pp. 699-714.

Wand, N, Smith, DA, Wilkinson, A, Rushton, A, Busby, SJW, Styles, I & Neely, RK 2019, '', Nucleic Acids Research, vol. 47, no. 12, gkz212, pp. e68.

Guerrero Montero, I, Richards, KL, Jawara, C, Browning, DF, Peswani, AR, Labrit, M, Allen, M, Aubry, C, Dav茅, E, Humphreys, DP, Busby, SJW & Robinson, C 2019, '', Biotechnology and Bioengineering, vol. 116, no. 12, pp. 3282-3291.

Comment/debate

Busby, SJW 2021, '', Proceedings of the National Academy of Sciences, vol. 118, no. 30, e2110640118.

Review article

Browning, DF, Butala, M & Busby, SJW 2019, '', Journal of Molecular Biology, vol. 431, no. 20, pp. 4067-4077.

Expertise

Bacterial genomes: particularly genes that enable bacteria to survive in stressful habitats and genes that make bacteria dangerous to humans

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Expertise

bacterial genomes; genes that enable bacteria to survive in stressful habitats; genes that make bacteria dangerous to humans; 

bacteria and their effects; molecular mechanisms that make life; organisation of UK Science; biophysics and biochemistry

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