Miss Victoria Homer

Miss Victoria Homer

Cancer Research UK Clinical Trials Unit
Senior Biostatistician

Contact details

Telephone
+44 (0) 121 414 3410
Email
v.s.homer@bham.ac.uk
Address
Cancer Research UK Clinical Trials Unit (CRCTU)
University 麻豆精选
Edgbaston
Birmingham
B15 2TT
UK

Victoria is a senior biostatistician at the Cancer Research Clinical Trials Unit (CRCTU) specialising in early phase clinical trials, Bayesian methodology, and trials in (ultra-)rare populations. She is the deputy director of the MRC-NIHR UK Rare Disease Research Platform CAPTIVATE node for trials methodology in rare diseases.

Qualifications

  • MSc Medical Statistics 2019 (University of Leicester)
  • BSc Mathematics (Hons) 2018 (University 麻豆精选) 

Biography

Victoria joined the Cancer Research UK Clinical Trials Unit (CRCTU) after completing the MSc Medical Statistics at the University of Leicester and is now a senior statistician within the unit.  She is involved in the design, supervision, analysis and reporting of clinical trials in a variety of oncology and non-oncology clinical areas in both adult and paediatric populations.  She has experience in all phases of trial from first-in-human and dose finding trials to randomised phase III trials of investigational medicinal products, devices, and advanced and cellular therapies. 

Victoria’s work focuses on early phase dose finding and proof of activity clinical trials, Bayesian methodology, and trials in rare diseases. She has a keen interest in improving efficiency in trials, mainly through adaptive designs, novel dose finding methods, and hierarchical and repeated measures analysis. 

Moreover, Victoria is the deputy director of the MRC-NIHR UK Rare Disease Research Platform CAPTIVATE node for trials methodology in rare diseases. This challenge node is aiming to develop innovative clinical trial designs that enable the efficient evaluation of treatments for rare diseases with limited numbers of participants such that the designs and data are acceptable to patients and participants, regulators, and policy makers.

Teaching

MSc Clinical Trials
Module lead for Early Phase Clinical Trials

Other activities

Victoria was recently involved in the Early Development Estimands Nexus of the Oncology Estimand Working Group to develop guidance on the implementation of estimands in phase Ia (dose finding) and Ib (dose confirmatory) trials and sits on external Safety and Data Monitoring Committees for trials at other trials units.

Publications

Recent publications

Article

Al-Shakhshir, S, Quraishi, MN, Mullish, B, Patel, A, Vince, A, Rowe, A, Homer, V, Jackson, N, Gyimah, D, Shabir, S, Manzoor, S, Cooney, R, Alrubaiy, L, Quince, C, van Schaik, W, Hares, MF, Beggs, AD, Efstathiou, E, Rimmer, P, Weston, C, Iqbal, T & Trivedi, PJ 2025, '', BMJ open, vol. 15, no. 1, e095392.

Dias, RP, Brock, K, Hu, K, Gupta, R, Martin, U, Peet, A, Wilson, M, Yu-Wai-Man, P, Wright, B, Mollan, S, Kulkarni, A, Meunier, I, Billingham, L, Nagy, Z, Rose, H, Koks, S, Zatyka, M, Astuti, D, Lynch, T, Morrison, KE, Barton, D, Cronier, S, Malpass, R, Evans, R, Malhi, A, Takhar, P, Lamb, A, Esteban-Bueno, G, M艂ynarski, W, Orssaud, C, Roubertie, A, Homer, V & Barrett, T 2025, '', BMJ open, vol. 15, no. 2, e091495.

Srinivasan, V, Homer, V, Barton, D, Clutterbuck-James, A, Jenkins, S, Potter, C, Brock, K, Logan, A, Smith, D, Bruce, L, Nagy, Z & Bach, SP 2024, '', PLoS ONE, vol. 19, no. 7, e0291285.

Thaller, M, Homer, V, Abbott, S, Hazlehurst, J, Mollan, SP & Sinclair, AJ 2024, '', Neuro-Ophthalmology.

Hirschfield, G, Arndtz, K, Kirkham, A, Chen, Y-Y, Fox, R, Rowe, A, Douglas-Pugh, J, Thorburn, D, Barnes, E, Aithal, GP, Hull, D, Bhandal, K, Olsen, K, Woodward, P, Lax, S, Newsome, P, Smith, D, Kallio, A, Adams, D, Homer, V & Weston, C 2024, '', Hepatology Communications, vol. 8, no. 5, e0426.

Thaller, M, Homer, V, Mollan, S & Sinclair, A 2023, '', Clinical and Experimental Ophthalmology.

Loke, J, Upasani, V, Gaskell, C, Fox, S, Fletcher, R, Thomas, C, Hopkins, L, Kumari, A, Tang, T, Yafai, E, Boucher, R, Homer, V, Toth, A, Chan, YLT, Randall, K, Rider, T, O'nions, J, Drew, V, Pillai, A, Dungarwalla, M, Murray, D, Khan, A, Wandroo, F, Moore, S, Krishnamurthy, P, Huang, YJ, Knapper, S, Byrne, J, Zhao, R, Craddock, C, Parry, H, Moss, P, Stanworth, SJ & Lowe, DM 2023, '', British Journal of Haematology, vol. 202, no. 3, pp. 498-503.

Englert, S, Mercier, F, Pilling, EA, Homer, V, Habermehl, C, Zimmermann, S & Kan-Dobrosky, N 2023, '', Pharmaceutical Statistics, vol. 22, no. 5, pp. 921-937.

Hyder, YF, Homer, V, Thaller, M, Byrne, M, Tsermoulas, G, Piccus, R, Mollan, SP & Sinclair, AJ 2023, '', American Journal of Ophthalmology, vol. 250, pp. 70-81.

Thaller, M, Homer, V, Mollan, SP & Sinclair, AJ 2023, '', Neurology, vol. 100, no. 15, pp. E1598-E1610.

Imran, R, Hassouna, T, Sur, G, Casey, A, Homer, V, Barton, D, Brock, K, Altarrah, K & Moiemen, N 2023, '', BMJ open, vol. 13, no. 9, e058006.

Mercier, F, Homer, V, Geng, J, Zhang, H, Englert, S, Kan-Dobrosky, N & Victor, A 2023, '', Statistics in Biopharmaceutical Research.

Thaller, M, Homer, V, Sassani, M, Mollan, SP & Sinclair, AJ 2023, '', Eye (London, England).

Bailey, S, Andr茅, N, Gandola, L, Massimino, M, Wheatley, K, Gates, S, Homer, V, Rutkowski, S & Clifford, S 2022, '', Cancers, vol. 14, no. 2, 374.

Comment/debate

Bailey, S, Andr茅, N, Gandola, L, Massimino, M, Wheatley, K, Gates, S, Homer, V, Rutkowski, S & Clifford, SC 2024, '', Cancers, vol. 16, no. 6, 1084.