Dr Si芒n Lax BSc (Hons), PhD

Dr Si芒n Lax

Cancer Research UK Clinical Trials Unit
Clinical Trial Facilitator

Contact details

Telephone
+44 (0)121 414 6369
Email
s.lax@bham.ac.uk
Address
Cancer Research UK Clinical Trials Unit (CRCTU)
University 麻豆精选
Edgbaston
Birmingham
B15 2TT
UK

Siân Lax’s current role is within the Cancer Research UK Clinical Trials Unit (CRCTU) where she acts as the first point of contact for clinical investigators wishing to work with the CRCTU.

Qualifications

  • PhD in Biochemistry, 2004
  • BSc (Hons) in Molecular and Cellular Biochemistry, 2001

Biography

As the Clinical Trial Facilitator, Siân, manages the CRCTU New Business process and provides assistance in obtaining research grants and contributes to writing clinical trial essential documents, publications and reports.

Before working at the CRCTU, Siân was a post-doctoral research fellow working in Professor Steve Watson’s Platelet Group, understanding the role of the platelet receptor CLEC-2 in regulating the severity of acute lung injury using in vivo models of lung inflammation and injury. Her previous post-doctoral work involved elucidating the in vivo role of hormones in lung injury and the role of mesenchymal stromal cells in lymphoid tissues following infection. Siân obtained her PhD from University 麻豆精选 in 2004 researching the function of Rho-kinase II in regulated keratinocyte differentiation.

Publications

Recent publications

Article

Bhaskaran, D, Savage, J, Patel, A, Collinson, F, Mant, R, Boele, F, Brazil, L, Meade, S, Buckle, P, Lax, S, Billingham, L & Short, S 2024, '', BMC Cancer, vol. 24, 83.

Kong, A, Kirkham, AJ, Savage, JS, Mant, R, Lax, S, Good, J, Forster, MD, Sacco, JJ, Schipani, S, Harrington, KJ, Yap, C & Mehanna, H 2024, '', BJC Reports, vol. 2, no. 1, 6.

Hirschfield, G, Arndtz, K, Kirkham, A, Chen, Y-Y, Fox, R, Rowe, A, Douglas-Pugh, J, Thorburn, D, Barnes, E, Aithal, GP, Hull, D, Bhandal, K, Olsen, K, Woodward, P, Lax, S, Newsome, P, Smith, D, Kallio, A, Adams, D, Homer, V & Weston, C 2024, '', Hepatology Communications, vol. 8, no. 5, e0426.

Fernando, IN, Lax, S, Bowden, SJ, Ahmed, I, Steven, JH, Churn, M, Brunt, AM, Agrawal, RK, Canney, P, Stevens, A & Rea, DW 2023, '', Clinical Oncology, vol. 35, no. 6, pp. 397-407.

Stapley, R, Smith, C, Haining, E, Bacon, A, Lax, S, Pisareva, V, Pisarev, A, Watson, S, Khan, A & Morgan, N 2021, '', Blood Advances, vol. 5, no. 2, pp. 377鈥�390.

Haining, E, Lowe, K, Wichaiyo, S, Kataru, RP, Nagy, Z, Kavanagh, D, Lax, S, Di, Y, Nieswandt, B, Ho-Tin-No茅, B, Mehrara, BJ, Senis, Y, Rayes, J & Watson, S 2021, '', Platelets, vol. 32, no. 3, pp. 352-367.

Chimen, M, Evryviadou, A, Box, CL, Harrison, MJ, Hazeldine, J, Dib, LH, Kuravi, SJ, Payne, H, Price, JMJ, Kavanagh, D, Iqbal, AJ, Lax, S, Kalia, N, Brill, A, Thomas, SG, Belli, A, Crombie, N, Adams, RA, Evans, S-A, Deckmyn, H, Lord, JM, Harrison, P, Watson, SP, Nash, GB & Rainger, GE 2020, '', Haematologica, vol. 105, no. 5, pp. 1248-1261.

Wichaiyo, S, Lax-Williams, S, Montague, S, Li, Z, Grygielska, B, Pike, J, Haining, E, Brill, A, Watson, S & Rayes, J 2019, '', Haematologica, vol. 104, no. 8, pp. 1648-1660.

Lax, S, Rayes, J, Thickett, DR & Watson, SP 2017, '', BMJ Open Respiratory Research, vol. 4, no. 1, e000257.

Lax, S, Rayes, J, Wichaiyo, S, Haining, EJ, Lowe, K, Grygielska, B, Laloo, R, Flodby, P, Borok, Z, Crandall, ED, Thickett, DR & Watson, SP 2017, '', American journal of physiology. Lung cellular and molecular physiology, vol. 313, no. 6, pp. L1016-L1029.

Rayes, J, Lax, S, Wichaiyo, S, Watson, S, Di, Y, Lombard, S, Grygielska, B, Smith, S, Skordilis, K & Watson, S 2017, '', Nature Communications, vol. 8, 2239.

Parekh, D, Patel, JM, Scott, A, Lax, S, Dancer, RCA, D'Souza, V, Greenwood, H, Fraser, WD, Gao, F, Sapey, E, Perkins, GD & Thickett, DR 2017, '', Critical care medicine, vol. 45, no. 2, pp. 282-289.

Hitchcock, JR, Cook, CN, Bobat, S, Ross, EA, Flores-Langarica, A, Lowe, KL, Khan, M, Dominguez Medina, C, Lax, S, Carvalho-Gaspar, M, Hubscher, S, Rainger, G, Cobbold, M, Buckley, CD, Mitchell, TJ, Mitchell, A, Jones, N, Van Rooijen, N, Kirchhofer, D, Henderson, IR, Adams, DH, Watson, SP & Cunningham, AF 2015, '', Journal of Clinical Investigation, vol. 125, no. 12, pp. 4429鈥�4446.

Letter

Fernando, IN, Lax, S & Ahmed, I 2020, '', Radiotherapy and Oncology, vol. 147, pp. 233.

Rayes, J, Jadoui, S, Lax, S, Gros, A, Wichaiyo, S, Ollivier, V, Denis, CV, Ware, J, Nieswandt, B, Jandrot-Perrus, M, Watson, SP & Ho-Tin-No茅, B 2018, '', Haematologica, vol. 103, no. 6, pp. e256-e258.