Dr Joshua Savage

Cancer Research UK Clinical Trials Unit
Trial Management Team Leader

Contact details

Telephone: +44 (0)121 415 8421
Fax: +44 (0)121 414 3529
Email: j.savage.1@bham.ac.uk

Address: Cancer Research UK Clinical Trials Unit (CRCTU)
University 麻豆精选
Edgbaston
Birmingham
B15 2TT
UK

Dr Joshua Savage is the Early Drug Development Trial Management Team Leader at the Cancer Research UK Clinical Trials Unit (CRCTU) at the University 麻豆精选.

Qualifications

PhD Pharmacology, University of Bristol, 2012
BSc (Hons) Biochemistry, University of Bristol, 2008

Biography

Joshua Savage graduated with a BSc. (Hons) in Biochemistry from the University of Bristol in 2008. Following this he was awarded a Biotechnology and Biological Sciences Research Council studentship to study for a PhD at the University of Bristol, investigating the functional role of protein kinases in thrombosis in heart disease in the laboratory of Professor Alastair Poole in 2008.

Joshua joined the Adult Late Phase Team (B Team) of the Cancer Research UK Clinical Trials Unit at the University 麻豆精选 in 2013, coordinating academically sponsored late phase trials in skin (UKMCC-01, SPOT) and head & neck cancer (CompARE). In 2015 he was promoted to Senior Trial Coordinator within the B team, then later that year moved to the Children鈥檚 Cancer Trials Team.听 Joshua worked primarily on international studies in the late phase solid tumour portfolio, focussing on Ewing鈥檚 sarcoma (EE2012, rEECur), rhabdomyosarcoma (RMS2005, FaR-RMS), and neuroblastoma (IMAT, HRNBL1), whilst also supporting the myeloid leukaemia study, MyeChild-01.

In 2018 Joshua was appointed as the EDD Trial Management Team Leader, and leads the trials team for a number of early phase cancer trials including the National Lung Matrix Trial, Tessa Jowell BRAIN MATRIX,听ANICCA-Class II and ARISTOCRAT.

Joshua is the module lead of the Preparation and Set-up for a Clinical Trial module in MSc Clinical Trials.

Teaching

MSc Clinical Trials

Other activities

(October 2021 - present)
MRC-NIHR TMRP Stratified Medicine Working Group Steering Committee (May 2020 - Present)
(June 2021 – present)

Publications

Highlight publications

Middleton, G, Robbins, HL, Fletcher, P, Savage, J, Mehmi, M, Summers, Y, Greystoke, A, Steele, N, Popat, S, Jain, P, Spicer, J, Cave, J, Shaw, P, Gilligan, D, Power, D, Fennell, D, Bajracharya, M, Mcbride, DJ, Maheswari, U, Frankell, AM, Swanton, C, Beggs, AD & Billingham, L 2025, '', npj Precision Oncology, vol. 9, no. 1, 67.

Young, RJ, Kirkham, A, Savage, J, Gaskell, C, Johnson, S, Dockrell, DH, Bower, M, Westwell, S, Bowman, C, Leahy, M, Woll, P & Billingham, L 2025, '', BMC Cancer, vol. 25, no. 1, 505.

Kong, A, Kirkham, AJ, Savage, JS, Mant, R, Lax, S, Good, J, Forster, MD, Sacco, JJ, Schipani, S, Harrington, KJ, Yap, C & Mehanna, H 2024, '', BJC Reports, vol. 2, no. 1, 6.

Bhaskaran, D, Savage, J, Patel, A, Collinson, F, Mant, R, Boele, F, Brazil, L, Meade, S, Buckle, P, Lax, S, Billingham, L & Short, S 2024, '', BMC Cancer, vol. 24, 83.

Middleton, G, Fletcher, P, Popat, S, Savage, J, Summers, Y, Greystoke, A, Gilligan, D, Cave, J, O鈥檙ourke, N, Brewster, A, Toy, E, Spicer, J, Jain, P, Dangoor, A, Mackean, M, Forster, M, Farley, A, Wherton, D, Mehmi, M, Sharpe, R, Mills, TC, Cerone, MA, Yap, TA, Watkins, TBK, Lim, E, Swanton, C & Billingham, L 2020, '', Nature, vol. 583, no. 7818, pp. 807-812.

Recent publications

Article

Mitchell, E, Goodman, K, Wakefield, N, Cochran, C, Cockayne, S, Connolly, S, Desai, R, Hartley, S, Lawton, S, Oatey, K, Rhodes, S, Savage, J, Taylor, J & Youssouf, N 2022, '', Trials, vol. 23, no. 1, 357.

Love, SB, Cafferty, F, Snowdon, C, Carty, K, Savage, J, Pallmann, P, McParland, L, Brown, L, Masters, L, Schiavone, F, Hague, D, Townsend, S, Amos, C, South, A, Sturgeon, K, Langley, R, Maughan, T, James, N, Hall, E, Kernaghan, S, Bliss, J, Turner, N, Tutt, A, Yap, C, Firth, C, Kong, A, Mehanna, H, Watts, C, Hills, R, Thomas, I, Copland, M, Bell, S, Sebag-Montefiore, D, Jones, R, Parmar, MKB & Sydes, MR 2022, '', Trials, vol. 23, no. 1, 757.

Watts, C, Savage, J, Patel, A, Mant, R, Wykes, V, Pohl, U, Bulbeck, H, Apps, J, Sharpe, R, Thompson, G, Waldman, AD, Ansorge, O & Billingham, L 2022, '', BMJ open, vol. 12, no. 9, e067123.

Menne, T, Slade, D, Savage, J, Johnson, S, Irving, J, Kearns, P, Plummer, R, Shenton, G, Veal, GJ, Vormoor, B, Vormoor, J & Billingham, L 2022, '', BMJ open, vol. 12, no. 3, e059872.

Williamson, SF, Grayling, MJ, Mander, AP, Noor, NM, Savage, JS, Yap, C & Wason, JMS 2022, '', Journal of Clinical Epidemiology, vol. 150, pp. 72-79.

Veenith, T, Fisher, BA, Slade, D, Rowe, A, Sharpe, R, Thickett, DR, Whitehouse, T, Rowland, M, Scriven, J, Parekh, D, Bowden, SJ, Savage, JS, Richards, D, Bion, J, Kearns, P, Gates, S & CATALYST Trial Investigators 2021, '', BMJ open, vol. 11, no. 11, e050202.

Middleton, G, Brock, K, Savage, J, Mant, R, Summers, Y, Connibear, J, Shah, R, Ottensmeier, C, Shaw, P, Lee, SM, Popat, S, Barrie, C, Barone, G & Billingham, L 2020, '', The Lancet Respiratory Medicine, vol. 8, no. 9, pp. 895-904.

Kong, A, Good, JS, Kirkham, A, Savage, J, Mant, R, Llewellyn, L, Parish, J, Spruce, R, Forster, M, Schipani, S, Harrington, K, Sacco, JJ, Murray, P, Middleton, G, Yap, C & Mehanna, H 2020, '', BMJ open, vol. 10, no. 3, e033009.

Middleton, G, Fletcher, P, Popat, S, Savage, J, Summers, Y, Greystoke, A, Gilligan, D, Cave, J, O'Rourke, N, Brewster, A, Toy, E, Spicer, J, Jain, P, Dangoor, A, Mackean, M, Forster, M, Farley, A, Wherton, D, Mehmi, M, Sharpe, R, Mills, TC, Cerone, MA, Yap, TA, Watkins, TBK, Lim, E, Swanton, C & Billingham, L 2020, '', Nature.

Williams, CM, Savage, JS, Harper, MT, Moore, SF, Hers, I & Poole, AW 2016, '', Platelets, vol. 27, no. 4, pp. 286-294.

Preprint

Love, SB, Cafferty, F, Snowdon, C, Carty, K, Savage, J, Pallmann, P, McParland, L, Brown, LJ, Masters, L, Schiavone, F, Hague, D, Townsend, S, Amos, C, South, A, Sturgeon, K, Langley, RE, Maughan, TS, James, N, Hall, E, Kernaghan, S, Bliss, J, Turner, NC, Yap, C, Firth, C, Kong, A, Mehanna, H, Watts, C, Hills, R, Thomas, I, Copland, M, Bell, SE, Tutt, ANJ, Sebag-Montefiore, D, Jones, R, Parmar, MKB & Sydes, MR 2022 '' Research Square.

Watts, C, Savage, J, Patel, A, Mant, R, Wykes, V, Pohl, U, Bulbeck, H, Apps, J, Sharpe, R, Thompson, G, Waldman, A, Ansorge, O, Billingham, L & Watts, C 2022 '' medRxiv.

Williamson, SF, Grayling, MJ, Mander, AP, Noor, N, Savage, J, Yap, C & Wason, JMS 2022 '' SSRN Electronic Journal, SSRN.

Veenith, T, Fisher, BA, Slade, D, Rowe, A, Sharpe, R, Thickett, DR, Whitehouse, T, Rowland, M, Scriven, J, Parekh, D, Bowden, SJ, Savage, JS, Richards, D, Bion, J, Kearns, P & Gates, S 2021 '' medRxiv, pp. 1-15.

Menne, T, Slade, D, Savage, J, Johnson, S, Irving, JAE, Kearns, PR, Plummer, R, Shenton, G, Veal, GJ, Vormoor, B, Vormoor, J & Billingham, L 2021 '' medRxiv.