Professor Larissa Fabritz

Professor Larissa Fabritz

Department of Cardiovascular Sciences
Honorary Professor

Contact details

Telephone
+44 (0)121 41 46938 (lab)
Telephone (2)
+44 (0)121 41 48259 (office)
Email
l.fabritz@bham.ac.uk
Address
Cardiovascular Sciences
College of Medicine and Health
University 麻豆精选
Edgbaston
Birmingham
B15 2TT
UK

Professor Larissa Fabritz studies novel mechanisms of heart disease and performs translational research towards mechanism-based therapies of cardiovascular diseases. As a clinical consultant, she sees patients in the Department of Cardiology at UHB. Larissa engages in research on molecular mechanisms of cardiomyopathies and arrhythmias as well as molecular cardiovascular imaging with her working group at the University 麻豆精选 and collaborations throughout Europe and North America.

Professor Fabritz is also Birmingham Principal Investigator for the  project. This is a major international research programme which will develop a precise method to diagnose atrial cardiomyopathy, thereby providing clinicians with individualised clinical patient data to predict a patient's likelihood of suffering from subclinical AF, their future risk of AF and their overall risk of ischemic stroke with an accuracy that surpasses any currently available instrument.

Qualifications

  • 2016 Fellow of the Royal College of Physicians London
  • 2012 Fellow of the European Society of Cardiology
  • 2012 Habilitation Internal Medicine “Towards molecular mechanism-based therapy of cardiomyopathies and arrhythmias”
  • 2011 GMC accreditation
  • 2010 Board Certification in Medicine
  • 1998 Thesis summa cum laude
  • 1997 Graduation from Medical School

Teaching

  • MBChB
  • BMedSci
  • MRes Cardiovascular Sciences

Professor Fabritz is currently Cardiology Specialty Lead for Year 4 MBChB and Cardiology Specialty Lead for the Academic In Day (Year 5 MBChB)

Postgraduate supervision

  • PhD supervisor
  • MD supervisor

Current students are listed on the group webpage.

Professor Fabritz has supervised MD and PhD students in Germany and the UK and offers translational and interdisciplinary cardiovascular research projects on various topics of heart failure and arrhythmias, cardiomyopathies and sudden death with opportunities for engagement in international collaborations. If you are interested in an MD or PhD in these areas, please contact Professor Fabritz via email including your CV.

Research Associate and Postdoctoral positions are currently available. Please email your application to L.Fabritz@bham.ac.uk including your CV.

Research

  • Molecular mechanisms of arrhythmias and cardiomyopathies
  • Molecular mechanisms of atrial fibrillation and atrial thrombosis
  • Sodium channel dysfunction
  • Desmosomal proteins
  • Effects of ageing and exercise on arrhythmia and cardiomyopathy
  • Translation of preclinical research into clinical trials
  • Personalised medicine and management of care in patients with atrial fibrillation using a variety of innovative tools and techniques
  • Biomarkers of cardiomyopathy and arrhythmia
  • Big data and machine learning techniques for cardiovascular data
  • Development of mobile apps for adherent therapy and patient engagement
  • Screening for atrial fibrillation including wearables

 

Professor Fabritz is also linked to the below research groups:

Other activities

  • Honorary Consultant in the , Fellow of the Royal College of Physicians
  • Institute for Cardiovascular Sciences Executive Committee, Internal Member for Impact and EDI
  • Institute for Cardiovascular Science Promotion Committee, Internal Member
  • Institute of Metabolism and Systems Research Promotion Committee, External Member
  • Nucleus member , liason person of European Heart Rhythm Association
  • Selection Committee of Oskar-Lapp Research Scholarship of German Cardiac Society
  • Past-chair, Nucleus German Cardiac Society Working Group of Molecular Cardiology, Spokesperson 2015-2017
  • DFG SFB and BHF Chair Site Visit Committee Member 2015, 2017, 2018
  • British Heart Foundation Committee for Project Grants, Member from 3rd quarter 2019
  •  - Characterizing Atrial fibrillation by Translating its Causes into Health Modifiers in the Elderly

Publications

Recent publications

Article

Chua, W, Khashaba, A, Canagarajah, H, Nielsen, JC, di Biase, L, Haeusler, KG, Hindricks, G, Mont, L, Piccini, J, Schnabel, RB, Schotten, U, Wienhues-Thelen, U-H, Zeller, T, Fabritz, L & Kirchhof, P 2024, '', Europace, vol. 26, no. 2, euae028.

Fabritz, L, Fortmueller, L, Gehmlich, K, Kant, S, Kemper, M, Kucerova, D, Syeda, F, Faber, C, Leube, R, Kirchhof, P & Krusche, CA 2024, '', Biomedicines, vol. 12, no. 5, 985.

Linz, D, Andrade, JG, Arbelo, E, Boriani, G, Breithardt, G, Camm, AJ, Caso, V, Nielsen, JC, De Melis, M, De Potter, T, Dichtl, W, Diederichsen, SZ, Dobrev, D, Doll, N, Duncker, D, Dworatzek, E, Eckardt, L, Eisert, C, Fabritz, L, Farkowski, M, Filgueiras-Rama, D, Goette, A, Guasch, E, Hack, G, Hatem, S, Haeusler, KG, Healey, JS, Heidbuechel, H, Hijazi, Z, Hofmeister, LH, Hove-Madsen, L, Huebner, T, K盲盲b, S, Kotecha, D, Malaczynska-Rajpold, K, Merino, JL, Metzner, A, Mont, L, Ng, GA, Oeff, M, Parwani, AS, Puererfellner, H, Ravens, U, Rienstra, M, Sanders, P, Scherr, D, Schnabel, R, Schotten, U, Sohns, C, Steinbeck, G, Steven, D, Toennis, T, Tzeis, S, van Gelder, IC, van Leerdam, RH, Vernooy, K, Wadhwa, M, Wakili, R, Willems, S, Witt, H, Zeemering, S & Kirchhof, P 2024, '', Europace, vol. 26, no. 4, euae070.

Khan, N, Steeds, R, Kyte, D, Fabritz, L, Collis, P, Chua, WWL, Stubbs, C, Mehta, S, Sun, Y, Nulty, M, Kirkham, K & Cotton, JM 2024, '', BMJ open, vol. 14, no. 6, e086587.

Reyat, J, Sommerfeld, L, O'Reilly, M, Roth Cardoso, V, Thiemann, E, Khan, A, O'Shea, C, Harder, S, M眉ller, C, Barlow, J, Stapley, R, Chua, WWL, Kabir, N, Grech, O, Hummel, O, H眉bner, N, Kaab, S, Mont, L, Hatem, SN, Winters, J, Zeemering, S, Morgan, N, Rayes, J, Gehmlich, K, Stoll, M, Brand, T, Schweizer , M, Piasecki, A, Schotten, U, Gkoutos, G, Lorenz, K, Cuello, F, Kirchhof, P & Fabritz, L 2024, '', Cardiovascular Research.

Rinn茅, S, Kiper, AK, Jacob, R, Ortiz-Bonnin, B, Schindler, RFR, Fischer, S, Komadowski, M, deMartino, E, Schafer, MK-H, Cornelius, T, Fabritz, L, Helker, CSM, Brand, T & Decher, N 2024, '', iScience.

Sommerfeld, LC, Holmes, AP, Yu, TY, O'Shea, C, Kavanagh, DM, Pike, JM, Wright, T, Syeda, F, Aljehani, A, Kew, T, Cardoso, VR, Kabir, SN, Hepburn, C, Menon, PR, Broadway鈥怱tringer, S, O'Reilly, M, Witten, A, Fortmueller, L, Lutz, S, Kulle, A, Gkoutos, GV, Pavlovic, D, Arlt, W, Lavery, GG, Steeds, R, Gehmlich, K, Stoll, M, Kirchhof, P & Fabritz, L 2024, '', The Journal of Physiology.

Rillig, A, Eckardt, L, Borof, K, Camm, AJ, Crijns, HJGM, Goette, A, Breithardt, G, Lemoine, MD, Metzner, A, Rottner, L, Schotten, U, Vettorazzi, E, Wegscheider, K, Zapf, A, Heidbuchel, H, Willems, S, Fabritz, L, Schnabel, RB, Magnussen, C & Kirchhof, P 2024, '', Europace, vol. 26, no. 6, euae121.

Aljehani, A, Baig, S, Kew, T, Kalla, M, Sommerfeld, LC, Murukutla, VA, Fabritz, L & Steeds, RP 2024, '', Biomedicines, vol. 12, no. 2, 328.

Chua, W, Cardoso, VR, Guasch, E, Sinner, MF, Al-Taie, C, Brady, P, Casadei, B, Crijns, HJGM, Dudink, EAMP, Hatem, SN, K盲盲b, S, Kastner, P, Mont, L, Nehaj, F, Purmah, Y, Reyat, JS, Schotten, U, Sommerfeld, LC, Zeemering, S, Ziegler, A, Gkoutos, GV, Kirchhof, P & Fabritz, L 2023, '', Scientific Reports, vol. 13, no. 1, 16743.

Aljehani, A, Kew, T, Baig, S, Cox, H, Sommerfeld, LC, Ensam, B, Kalla, M, Steeds, RP & Fabritz, L 2023, '', BMC Cardiovascular Disorders, vol. 23, no. 1, 14.

Schnabel, RB, Marinelli, EA, Arbelo, E, Boriani, G, Boveda, S, Buckley, CM, Camm, AJ, Casadei, B, Chua, W, Dagres, N, de Melis, M, Desteghe, L, Diederichsen, SZ, Duncker, D, Eckardt, L, Eisert, C, Engler, D, Fabritz, L, Freedman, B, Gillet, L, Goette, A, Guasch, E, Svendsen, JH, Hatem, SN, Haeusler, KG, Healey, JS, Heidbuchel, H, Hindricks, G, Hobbs, FDR, H眉bner, T, Kotecha, D, Krekler, M, Leclercq, C, Lewalter, T, Lin, H, Linz, D, Lip, GYH, L酶chen, ML, Lucassen, W, Malaczynska-Rajpold, K, Massberg, S, Merino, JL, Meyer, R, Mont, L, Myers, MC, Neubeck, L, Niiranen, T, Oeff, M, Oldgren, J, Potpara, TS, Psaroudakis, G, P眉rerfellner, H, Ravens, U, Rienstra, M, Rivard, L, Scherr, D, Schotten, U, Shah, D, Sinner, MF, Smolnik, R, Steinbeck, G, Steven, D, Svennberg, E, Thomas, D, True Hills, M, van Gelder, IC, Vardar, B, Pal脿, E, Wakili, R, Wegscheider, K, Wieloch, M, Willems, S, Witt, H, Ziegler, A, Daniel Zink, M, Willems, S, Witt, H, Ziegler, A, Daniel Zink, M & Kirchhof, P 2023, '', Europace, vol. 25, no. 1, pp. 6-27.

Kany, S, Cardoso, VR, Bravo, L, Williams, JA, Schnabel, R, Fabritz, L, Gkoutos, GV & Kirchhof, P 2022, '', Heart.

O'Reilly, M, Sommerfeld, LC, O'Shea, C, Broadway-Stringer, S, Andaleeb, S, Reyat, JS, Kabir, SN, Stastny, D, Malinova, A, Delbue, D, Fortmueller, L, Gehmlich, K, Pavlovic, D, Skryabin, BV, Holmes, AP, Kirchhof, P & Fabritz, L 2022, '', EP Europace.

Review article

ESC Task Force, Glikson, M, Nielsen, JC, Kronborg, MB, Michowitz, Y, Auricchio, A, Barbash, IM, Barrabes, JA, Boriani, G, Braunschweig, F, Brignole, M, Burri, H, Coats, AJS, Deharo, JC, Delgado, V, Diller, GP, Israel, CW, Keren, A, Knops, RE, Kotecha, D, Leclercq, C, Merkely, B, Starck, C, Thylen, I, Tolosana, JM, Leyva, F, Linde, C, Abdelhamid, M, Aboyans, V, Arbelo, E, Asteggiano, R, Bar贸n-Esquivias, G, Bauersachs, J, Biffi, M, Birgersdotter-Green, U, Bongiorni, MG, Borger, MA, Celutkien臈, J, Cikes, M, Daubert, JC, Drossart, I, Ellenbogen, K, Elliott, PM, Fabritz, L, Falk, V, Fauchier, L, Fern谩ndez-Aviles, F, Foldager, D, Gadler, F, De Vinuesa, PGG, Gorenek, B, Guerra, JM, Haugaa, KH, Hendriks, J, Kahan, T, Katus, HA, Konradi, A, Koskinas, KC, Law, H, Lewis, BS, Linker, NJ, L酶chen, M-L, Lumens, J, Mascherbauer, J, Mullens, W, Nagy, KV, Prescott, E, Raatikainen, P, Rakisheva, A, Reichlin, T, Ricci, RP, Shlyakhto, E, Sitges, M, Sousa-Uva, M, Sutton, R, Suwalski, P, Svendsen, JH, Touyz, RM, Van Gelder, IC, Vernooy, K, Waltenberger, J, Whinnett, Z & Witte, KK 2022, '', Europace, vol. 24, no. 1, pp. 71-164.