Professor Katja Gehmlich

Katja Gehmlich

Department of Cardiovascular Sciences
Professor of Molecular Cardiology

Contact details

Telephone
+44 (0) 121 414 8529
Email
k.gehmlich@bham.ac.uk
Address
Cardiovascular Sciences
College of Medicine and Health
Univeristy 麻豆精选
Edgbaston
Birmingham
B15 2TT

Professor Katja Gehmlich is interested in how genetic variants in genes coding for proteins involved in biomechanical stress signalling cause inherited cardiac conditions (cardiomyopathies). She employs molecular, biophysical, cellular and in vivo models in her research. In particular she is interested in using induced pluripotent stem cell derived cardiomyocytes in her research.

Qualifications

  • PhD (Dr. rer. nat.) in Cell Biology 2005
  • Diploma (MSc equivalent) in Chemistry 2001

Biography

Professor Katja Gehmlich graduated with a Diploma in Chemistry (with Molecular and Cellular Biology) from the University of Potsdam, Germany in 2001. She received a PhD in Cell Biology from the same university in 2005.

Professor Gehmlich came to the UK for her postdoctoral training and work at the University of Manchester (2005-2007), University College London (2007 – 2010) and University of Oxford (2010 – 2013).

She was awarded a British Heart Foundation Intermediate Basic Science Research Fellowship (2013 – 2020). She received the title University Research Lecturer from the University of Oxford in 2016 and became Associate Professor in 2018. She has an active secondary affiliation with Cardiovascular Medicine in the Radcliffe Department of Medicine at the University of Oxford.

In 2019, she became Associate Professor in Cardiovascular Science at the Department of Cardiovascular Sciences, University 麻豆精选, also Visiting Associate Professor at the University of Oxford. In 2024, she was promoted to Professor of Molecular Cardiology.

She has a long standing interest in the cardiac system with focus on inherited cardiac conditions (cardiomyopathies) and bio-mechanical stress signalling.

Teaching

Professor Katja Gehmlich has extensive experience in supervision of undergraduate research students.

Postgraduate supervision

Professor Katja Gehmlich has supervised numerous postgraduate students (2 completed, one active).

She accepts PhD students in her group, e.g. with interest in projects using induced pluripotent stem cell derived cardiomyocytes to understand biomechanical stress signalling in the heart.

Research

Professor Katja Gehmlich has a long standing interest into striated muscle systems.

Her research pursues the following questions:

  • What is the role of certain signalling proteins in the heart?
  • What are the consequences of genetic variants in these proteins? How do they cause inherited cardiac conditions (called cardiomyopathies)?
  • Can these diseases be modelled with the help of in vivo models and/or induced pluripotent stem cell derived cardiomyocytes?


Professor Gehmlich collaborates with other research groups such as:

  • Heart Failure and Arrhythmia Cluster, Institute of Cardiovascular Sciences, University 麻豆精选
  • with the Radcliffe Department of Medicine, University of Oxford
  • Biomechanical stress signalling in the heart and its role in cardiomyopathies

Other activities

Professor Katja Gehmlich is peer reviewer for various International journals and funding agencies. She is member of the editorial board of Biophysical Reviews.

Publications

Recent publications

Article

Leinhos, L, Robinson, P, Poloni, G, Broadway-Stringer, S, Beglov, J, Lokman, AB, Douglas, G, Nuthay, S, Fonseka, O, Schmid, M, Singer, E, Hooper, C, Thomson, K, Bagnall, RD, Ingles, J, Semsarian, C, Ormondroyd, E, Toepfer, CN, Davies, B, Redwood, CR, Watkins, H & Gehmlich, K 2025, '', Scientific Reports.

Wang, Z, Cao, G, Collier, MP, Qiu, X, Broadway-Stringer, S, 艩aman, D, Ng, JZY, Sen, N, Azad, A, Hooper, C, Zimmerman, J, McDonough, MA, Brem, J, Rabe, P, Song, H, Alderson, TR, Schofield, CJ, Bolla, JR, Djinovic-Carugo, K, F眉rst, DO, Warscheid, B, Degiacomi, MT, Allison, TM, Hochberg, GKA, Robinson, CV, Gehmlich, K & Benesch, JLP 2025, '', Nature Communications.

Chunthorng-Orn, J, Noureddine, M, Dawson, P, Lord, SO, Ng, J, Boyton, L, Gehmlich, K, Mohammed, F & Lai, Y-C 2025, '', International Journal of Molecular Sciences, vol. 26, no. 8, 3921.

Noureddine, M, Mikolajek, H, Morgan, N, Denning, C, Loughna, S, Gehmlich, K & Mohammed, F 2025, '', Journal of General Physiology, vol. 157, no. 2, e202413684.

Roy, A, Cumberland, M, O'Shea, C, Holmes, A, Kalla, M, Gehmlich, K, Geberhiwot, T & Steeds, R 2024, '', Current cardiology reports.

Patel, L, Roy, A, Barlow, J, O'Shea, C, Nieves, D, Azad, A, Hall, C, Davies, B, Rath, P, Pavlovic, D, Chikermane, A, Geberhiwot, T, Steeds, R & Gehmlich, K 2024, '', Molecular Genetics and Metabolism, vol. 143, no. 1-2, 108575.

Roy, A, Patel, L, Yuan, M, O'Shea, C, Alvior, AMB, Charalambides, M, Moxon, D, Baig, S, Bunting, KV, Gehmlich, K, Geberhiwot, T & Steeds, R 2024, '', International Journal of Cardiology, vol. 409, 132212.

Fabritz, L, Fortmueller, L, Gehmlich, K, Kant, S, Kemper, M, Kucerova, D, Syeda, F, Faber, C, Leube, R, Kirchhof, P & Krusche, CA 2024, '', Biomedicines, vol. 12, no. 5, 985.

St酶le, TP, Lunde, M, Gehmlich, K, Christensen, G, Louch, WE & Carlson, CR 2024, '', Cells, vol. 13, no. 11, 947.

McKay, EJ, Luijten, I, Broadway-Stringer, S, Thomson, A, Weng, X, Gehmlich, K, Gray, GA & Semple, RK 2024, '', Disease Models & Mechanisms.

Gehmlich, K & Krause, S 2024, '', Data, vol. 9, no. 7, 84.

Cumberland, M, Euchner, J, Azad, A, Vo, NTN, Kirchhof, P, Holmes, A, Denning, C & Gehmlich, K 2024, '', F1000Research, vol. 12, 1224.

Reyat, J, Sommerfeld, L, O'Reilly, M, Roth Cardoso, V, Thiemann, E, Khan, A, O'Shea, C, Harder, S, M眉ller, C, Barlow, J, Stapley, R, Chua, WWL, Kabir, N, Grech, O, Hummel, O, H眉bner, N, Kaab, S, Mont, L, Hatem, SN, Winters, J, Zeemering, S, Morgan, N, Rayes, J, Gehmlich, K, Stoll, M, Brand, T, Schweizer , M, Piasecki, A, Schotten, U, Gkoutos, G, Lorenz, K, Cuello, F, Kirchhof, P & Fabritz, L 2024, '', Cardiovascular Research.

Sommerfeld, LC, Holmes, AP, Yu, TY, O'Shea, C, Kavanagh, DM, Pike, JM, Wright, T, Syeda, F, Aljehani, A, Kew, T, Cardoso, VR, Kabir, SN, Hepburn, C, Menon, PR, Broadway鈥怱tringer, S, O'Reilly, M, Witten, A, Fortmueller, L, Lutz, S, Kulle, A, Gkoutos, GV, Pavlovic, D, Arlt, W, Lavery, GG, Steeds, R, Gehmlich, K, Stoll, M, Kirchhof, P & Fabritz, L 2024, '', The Journal of Physiology.

Review article

Thompson, SE, Roy, A, Geberhiwot, T, Gehmlich, K & Steeds, R 2025, '', Biomedicines.