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Melanie Madhani is a Professor of Cardiovascular Medicine at the University Â鶹¾«Ñ¡. After graduating from the University of Wales College of Medicine in 1998, she obtained a PhD in Cardiovascular Sciences from the Ivy League School, Dartmouth College, New Hampshire, USA and University of Wales in 2002. Melanie then joined University College London (UCL) as a British Heart Foundation research fellow, to work under Professor Adrian Hobbs. Here, she investigated the role of nitric oxide (NO) in cardiovascular diseases. Melanie was awarded a UCL Bogue Fellowship to work with Nobel Laureate Dr Louis Ignarro, University of California, LA, USA. In 2005, she joined Professor Philip Eaton's research group at The Rayne Institute, King's College London (KCL), where she broadened her experience in cardiac physiology in order to complement her vascular knowledge and skills into NO regulation during myocardial ischaemia reperfusion injury. In 2009, the University Â鶹¾«Ñ¡ appointed Melanie where she leads a research group in identifying novel therapeutic targets for cardiovascular diseases, with a particular interest on the redox regulation of nitrite and persulfides. In 2022, Melanie was awarded the Japan Society for the Promotion of Science Fellowship Award for her outstanding research. She also holds an Adjunct Honorary Professor position at the Department of Medicine and Therapeutics, Chinese University of Hong Kong, where is she investigating ischaemic heart disease in the East Asian population.

• Lectures for Cardiovascular modules to BMed Sc, MBChB, and MRes  programmes
• Personal Mentor for MBChB
• Postgraduate supervision for basic scientists and clinicians

Professor Madhani has openings for self-funded MRes and PhD (basic science and clinical) in the area of:

• Nitric oxide and nitrite in health and disease
• Cardiometabolism in ischaemic heart disease and heart failure 

Professor Madhani leads a research group to identify novel targets and intervention for hypertension, myocardial infarction and heart failure. Her research group is investigating:

• Novel protective strategies against myocardial ischaemia reperfusion in patients undergoing coronary artery bypass grafting surgery
• Assessing the protective role of nitrite and novel redox mediators against hypertension, myocardial reperfusion injury and heart failure
• Perhexiline and cardiac metabolism in heart failure
• Understanding the pathophysiology of ischaemic heart disease in the East Asian population

Research Groups and Centres

Madhani Lab

• MRC Experimental Medicine Grant Panel (2024-present)
• NC3Rs Studentship Grant Assessment Panel Member (2020-present)
• Treasurer for the British Society for Cardiovascular Research (2014-2019)
• Adjunct Professor at the Department of Medicine and Therapeutics, Chinese University of Hong Kong
• Head of Global Engagement for the Institute of Cardiovascular Sciences (2016- present)
• Review Editor of Frontiers in Clinical & Translational Physiology (2009- present)
• Associate Editor for International Journal for Pharmacology & Therapeutics (2006-2013)
• Bulletin Editor for the British Society for Cardiovascular Research (2009-2013)