麻豆精选

• Fellow of the Higher Education Academy
• Postgraduate Certificate in Academic Practice (2014)
• Foundation of Learning and Teaching in Higher Education, 2012
• PhD in Immunology, 1998
• BSc Hons Applied Biology, 1994

Professor Lalor's undergraduate degree included a year in research hosted in the laboratory of Professor Nash which developed her interest in the processes of inflammatory cell recruitment across the vasculature. This was enhanced by Trish's PhD studies in Professor Nash’s group where she investigated the contribution that platelets play in white blood cell adhesion and migration under physiological shear.

Professor Lalor was able to advance these studies in her postdoctoral projects to understand the unique phenotype of human hepatic sinusoidal endothelial cell and how these cells participate in the cellular regulation of human liver inflammation and fibrosis during liver disease. She now continues to work closely with clinical colleagues in the Centre for Liver and Gastroenterology Research to use the well validated cohorts of human samples available in our unit to develop human cell and tissue based models to understand the regulation of both acute and chronic liver injury.

Trish remains particularly interested in the contribution of sinusoidal endothelial cells and platelets to hepatic inflammation. Professor Lalor also has cross-disciplinary programmes of research that use novel biophysical and chemical tools to understand and potentially treat complex liver disease. She has a particular interest in metabolic liver disease and fibrosis.

Professor Lalor has funding from MRC and Wellcome schemes, BBSRC and The European Union to support her research and she also works with major pharmaceutical companies on collaborative projects. Her team is composed of both scientific and clinical researchers and she supervises PhD students funded on national and international schemes.

• Module co-ordinator for Liver Cell Biology in BMedSc year 3 with responsibility for delivering teaching and designing and marking assessments. Trish also teaches on the Stem cell module for year 2 and is  a personal tutor on this course.  Medical Science BMedSc
• Clinical Science Bmedsci, supervisor for intercalating student projects and lecturing on the lier and GI module for this course Clinical Science BMedSc - Intercalated Degree
• Supervisor for BMedSc3, research student projects and dissertation
• Birmingham Foundation Academy, tutor for lectures and practical sessions for students enrolled on the Medical Sciences pathway Medical Sciences Pathway
• Medicine and Surgery MBChB: student tutor, lecturer and mentor for SSA activities
• PSIBS : lecturing and project supervision – Physical Sciences for Health

Professor Lalor has several current students on clinical, academic and industry funded programmes.

If you are interesting in studying any of these subject areas please contact Professor Patricia Lalor directly, or for any general doctoral research enquiries, please email mds-gradschool@contacts.bham.ac.uk.

For a full list of available Doctoral Research opportunities, please visit our Doctoral Research programme listings.

Research interests

• Inflammation
• Cell adhesion
• Endothelial biology
• Fibrogenesis
• Liver metabolism
• Alcohol-related liver injury
• NAFLD
• Toxic liver injury

Current projects

• Marie Curie ITN – DeLiver
• MRC CiC and WT ISSF – new therapeutic options in acute liver injury
• BBSRC/ GSK Collaborative Training Partnership : human liver models to investigate hepatic clearance mechanisms
• MRC Stratified Medicine Initiative – Minimising mortality in alcoholic hepatitis
• Novo Nordisk: Research collaboration in NAFLD pathogenesis
• Takeda : Collaborative research project in NASH

• Professor Lalor is a peer reviewer for major high impact, disciplinary journals including: Gastroenterology, PLosOne, Cell Transplantation, Gut, Hepatology, Journal of Leukocyte Biology, The American Journal of Transplantation, Inflammation Research, American Journal of Pathology, Liver International and Liver Transplantation.
• NC3Rs Fellowship Grant committee member
• Professor Lalor also also a peer reviews for funding applications (eg BHF Intermediate Fellowships, MRC Training Fellowships, MRC New Investigators Research Grants, Netherlands Organization for Scientific Research (NWO) grants, Austrian Science Fund (FWF) project grants, Agency for Science, Technology and Research (A*STAR) Singapore project grants)
• Professor Lalor has run public engagement events for Think Tank, The Big Bang Fair and The QEHB showcase days