Professor Adam Croft BSc (Hons), MBChB, PhD, MRCP (UK)

Adam Croft

Department of Inflammation and Ageing
Head of Department of Inflammation and Ageing
Professor of Translational Rheumatology
Kennedy Trust for Rheumatology Research Senior Clinical Research Fellow, Versus Arthritis Chair of Rheumatology

Contact details

Address
Rheumatology Research Group
Department of Inflammation and Ageing
University 麻豆精选
Queen Elizabeth Hospital, Birmingham, B15 2WB

Adam is Head of Department of Inflammation and Ageing, a multidisciplinary research department of discovery scientists and clinicians, translating mechanisms which underpin inflammation into new treatments/pathways for inflammatory diseases. Adam is also a Professor of Translational Rheumatology and an Honorary Consultant Rheumatologist at Sandwell and West Birmingham Hospitals and University Hospital 麻豆精选 NHS Trusts. He is also the Versus Arthritis Chair of Rheumatology. 

His main research interest is the development of novel immunotherapies for patients with autoimmune rheumatic and chronic inflammatory diseases, with a particular interest in the development of stromal cell (fibroblast) specific targets. He has received funding from the Wellcome Trust and NIHR.

His clinical interests include management of both early and treatment resistant inflammatory arthritis. His research is supported by the Kennedy Trust for Rheumatology Research, Versus Arthritis and Wellcome Trust.

Qualifications

  • PG Cert Medical education 2018
  • PG Cert in Clinical Research Methodology 2015
  • MRCP (UK) 2012
  • MBChB 2009
  • PhD 2005
  • BSc (Hons) 2002

Teaching

  • Year 2 BMedSci Immunology tutorials

Postgraduate supervision

Dr Croft's main research interest is in the development of novel immunotherapies for patients with autoimmune rheumatic and chronic inflammatory diseases. He has a particular interest in the development of stromal cell specific targets. His clinical interests include management of both early and treatment resistant inflammatory arthritis. He is also interested in the management of rare systemic inflammatory diseases including vasculitis.

PhD opportunites are available within the Rheumatology Research Group

Other activities

Current

  • 2018- Member of Paediatric and adolescent rheumatology network
  • 2018- Member of Scientific Advisory Committee, NIHR Wellcome Trust Clinical Research facility, University 麻豆精选
  • 2016- UK country liaison to EMUNET EULAR advisory group (by competitive national appointment)
  • 2016- Member of West Midlands regional vasculitis network

Previous

  • 2015-2018 Chair of British Rheumatologists in Training Advisory Group and West Midlands regional representative (by competitive national appointment)
  • Member of British Society of Rheumatology Council
  • Member of Joint Specialty Committee at Royal College of Physicians
  • Member of rheumatology JRCTPB speciality advisory group
  • Member of Education and training subcommittee
  • 2016-2018 Member of Clinical Care Quality committee, British Society of Rheumatology (trainee representative)
  • 2016-2018 Member of Peer Review working group, British Society of Rheumatology (trainee representative)
  • 2013-2017 Royal college of Physicians Associate Clinical Tutor, Queen Elizabeth Hospital, Birmingham
  • 2012-2014 Associate Clinical Teaching Fellow, Queen Elizabeth Hospital, Birmingham
  • 2009-2013 Advanced Life Support Instructor, Resuscitation Council UK     

Publications

Recent publications

Article

Roche Fibroblast Network Consortium 2025, '', Nature Communications, vol. 16, no. 1, 5.

Rauber, S, Mohammadian, H, Schmidkonz, C, Atzinger, A, Soare, A, Treutlein, C, Kemble, S, Mahony, CB, Geisthoff, M, Angeli, MR, Raimondo, MG, Xu, C, Yang, K-T, Lu, L, Labinsky, H, Saad, MSA, Gwellem, CA, Chang, J, Huang, K, Kampylafka, E, Knitza, J, Bilyy, R, Distler, JHW, Hanlon, MM, Fearon, U, Veale, DJ, Roemer, FW, B盲uerle, T, Maric, HM, Maschauer, S, Ekici, AB, Buckley, CD, Croft, AP, Kuwert, T, Prante, O, Ca帽ete, JD, Schett, G & Ramming, A 2024, '', Nature Immunology.

Baruah, P, Marshall, JL, Nefla, M, Pucino, V, Adams, H, Turner, JD, Gilbert, S, Powell, E, Neag, G, Monksfield, P, Irving, RM, Croft, AP, Dumitriu, IE & Buckley, CD 2024, '', Frontiers in Endocrinology, vol. 15, 1397839.

Coyle, C, Ma, M, Abraham, Y, Mahony, CB, Steel, K, Simpson, C, Guerra, N, Croft, AP, Rapecki, S, Cope, A, Bowcutt, R & Perucha, E 2024, '', JCI Insight, vol. 9, no. 23, e182390.

Baruah, P, Mahony, C, Marshall, JL, Smith, CG, Monksfield, P, Irving, RI, Dumitriu, IE, Buckley, CD & Croft, AP 2024, '', British Journal of Cancer, vol. 130, no. 10, pp. 1659-1669.

Murillo-Saich, JD, Coras, R, Ramirez, J, Quesada-Masachs, E, Sala-Climent, M, Eschelbach, K, Mahony, CB, Celis, R, Armando, A, Quehenberger, O, Croft, AP, Kavanaugh, A, Chang, E, Ca帽ete, JD, Guma, M & Singh, A 2024, '', Arthritis & Rheumatology (Hoboken).

Ahmed, S, Mahony, CB, Torres, A, Murillo-Saich, J, Kemble, S, Cedeno, M, John, P, Bhatti, A, Croft, AP & Guma, M 2023, '', Arthritis Research & Therapy, vol. 25, no. 1, 176.

Khan, AO, Rodriguez-Romera, A, Reyat, JS, Olijnik, AA, Colombo, M, Wang, G, Wen, WX, Sousos, N, Murphy, LC, Grygielska, B, Perrella, G, Mahony, CB, Ling, RE, Elliott, NE, Karali, CS, Stone, AP, Kemble, S, Cutler, EA, Fielding, AK, Croft, AP, Bassett, D, Poologasundarampillai, G, Roy, A, Gooding, S, Rayes, J, Machlus, KR & Psaila, B 2023, '', Cancer Discovery, vol. 13, no. 2, pp. 364-385.

Reyat, JS, di Maio, A, Grygielska, B, Pike, J, Kemble, S, Rodriguez-Romero, A, Simoglou Karali, C, Croft, AP, Psaila, B, Sim玫es, F, Rayes, J & Khan, AO 2023, '', Frontiers in cardiovascular medicine, vol. 10.

Torres, A, Kang, S, Mahony, CB, Cede帽o, M, Oliveira, PG, Fernandez-Bustamante, M, Kemble, S, Laragione, T, Gulko, PS, Croft, AP, Sanchez-Lopez, E, Miyamoto, S & Guma, M 2023, '', Frontiers in immunology, vol. 14, 1103231.

Comment/debate

Bolton, C & Croft, AP 2024, '', Nature Reviews Rheumatology.

Hackland, A & Croft, AP 2023, '', Nature Reviews Rheumatology, vol. 19, no. 3, pp. 132-133.

Preprint

Accelerating Medicines Partnership RA/SLE Network 2025 '' bioRxiv.

Mueller, AA, Zou, AE, Marsh, L-J, Kemble, S, Nayar, S, Watts, GFM, Murphy, CL, Taylor, E, Major, T, Gardner, D, Buckley, CD, Wei, K, Raychaudhuri, S, Korsunsky, I, Filer, A, Croft, AP & Brenner, MB 2025 '' bioRxiv.

Review article

Karsdal, M, Cox, TR, Parker, AL, Willumsen, N, Sand, JMB, Jenkins, G, Hansen, HH, Oldenburger, A, Geillinger-Kaestle, KE, Larsen, AT, Black, D, Genovese, F, Eckersley, A, Heinz, A, Nystr枚m, A, Holm Nielsen, S, Bennink, L, Johannsson, L, Bay-Jensen, A-C, Orange, DE, Friedman, S, R酶pke, M, Fiore, V, Schuppan, D, Rieder, F, Simona, B, Borthwick, L, Skarsfeldt, M, Wennbo, H, Thakker, P, Stoffel, R, Clarke, GW, Kalluri, R, Ruane, D, Zannad, F, Mortensen, JH, Sinkeviciute, D, Sundberg, F, Coseno, M, Thudium, C, Croft, AP, Khanna, D, Cooreman, M, Broermann, A, Leeming, DJ, Mobasheri, A & Ricard-Blum, S 2025, '', Journal of Clinical Medicine, vol. 14, no. 6, 1856.