Professor Joao Pedro Magalhaes PhD

Joao Pedro Magalhaes

Department of Inflammation and Ageing
Professor of Molecular Biogerontology

Contact details

Email
j.p.magalhaes@bham.ac.uk
Twitter

Ageing has a profound impact on human society and modern medicine, yet it remains a major puzzle of biology. The goal of my work is to help understand the genetic, cellular, and molecular mechanisms of ageing. In the long term, I would like my work to help ameliorate age-related diseases and preserve health. No other biomedical field has so much potential to improve human health as research on the basic mechanisms of ageing.

Please visit our lab website for further details about our work and publications, or see my TEDx talk

Qualifications

Professor of Molecular Biogerontolgy:

  • PhD in Biological Sciences, 2004
  • Licentiate in Microbiology, 1999

Biography

TEDx talk
Ted-Ed lesson

Prof de Magalhaes graduated in Microbiology in 1999 from the Escola Superior de Biotecnologia in his hometown of Porto, Portugal, and then obtained his PhD in 2004 from the University of Namur in Belgium. Following a postdoc with genomics pioneer Prof George Church at Harvard Medical School in Boston, USA, in 2008 Prof de Magalhaes was recruited to the University of Liverpool in the UK to establish his own group on genomic approaches to ageing. In 2022, Prof de Magalhaes was recruited to the University 麻豆精选 as Chair of Molecular Biogerontology where he currently leads the Genomics of Ageing and Rejuvenation Lab [http://rejuvenomicslab.com/].

His lab studies the ageing process and how we can manipulate it to fend off age-related diseases and improve human health. The lab’s research integrates different strategies, but its focal point is developing and applying experimental and computational methods that help bridge the gap between genotype and phenotype, a major challenge of the post-genome era, and help decipher the human genome and how it regulates complex processes like ageing.

Notably, his lab is a world-leader in employing genomics and bioinformatics to study ageing with pioneering work in studying gene networks of ageing and in sequencing and analyzing genomes from long-lived species. Prof de Magalhaes has authored over 100 publications and given over 100 invited talks, including three TEDx talks. His research has also been widely featured in the popular press (BBC, CNN, the Washington Post, the Financial Times and many others).

Prof de Magalhaes is an advisor/consultant for various organizations, including nonprofit foundations, universities, investment funds and biotech companies. In the long-term. Prof de Magalhaes would like his work to contribute to the development of interventions that preserve health and combat disease by manipulating the ageing process

Publications

Recent publications

Article

Dos Santos, GA, Magdaleno, GDV & de Magalh茫es, JP 2024, '', Aging, vol. 16, no. 7, pp. 5796-5810.

Wang, X, Zhang, Y, Chen, K, Liang, Z, Ma, J, Xia, R, de聽Magalh茫es, JP, Rigden, DJ, Meng, J & Song, B 2024, '', Nucleic Acids Research, vol. 52, no. D1, pp. D203-D212.

Lagger, C, Ursu, E, Equey, A, Avelar, RA, Pisco, AO, Tacutu, R & de Magalh茫es, JP 2023, '', Nature Aging, vol. 3, no. 11, pp. 1446-1461.

de Magalh茫es, JP 2023, '', BioEssays.

Dos Santos, GA, Chatsirisupachai, K, Avelar, RA & de Magalh茫es, JP 2023, '', BMC Genomics, vol. 24, no. 1, 644.

Mikaeloff, F, Gelpi, M, Escos, A, Knudsen, AD, H酶gh, J, Benfield, T, de Magalh茫es, JP, Nielsen, SD & Neogi, U 2023, '', Aging Cell.

Vega Magdaleno, GD, Bespalov, V, Zheng, Y, Freitas, AA & Lourenco Rocha De Magalhaes, JP 2022, '', BMC Bioinformatics, vol. 23, no. 1, 10.

Tejada-martinez, D, Avelar, RA, Lopes, I, Zhang, B, Novoa, G, De Magalh茫es, JP, Trizzino, M & Malik, H (ed.) 2022, '', Molecular Biology and Evolution, vol. 39, no. 2, msab369.

Mikaeloff, F, Svensson Akusj盲rvi, S, Ikomey, GM, Krishnan, S, Sperk, M, Gupta, S, Magdaleno, GDV, Esc贸s, A, Lyonga, E, Okomo, MC, Tagne, CT, Babu, H, Lorson, CL, V茅gv谩ri, 脕, Banerjea, AC, Kele, J, Hanna, LE, Singh, K, De Magalh茫es, JP, Benfeitas, R & Neogi, U 2022, '', Communications Biology, vol. 5, no. 1, 27.

Liu, L, Song, B, Chen, K, Zhang, Y, De Magalh茫es, JP, Rigden, DJ, Lei, X & Wei, Z 2022, '', Methods, vol. 203, pp. 378-382.

Review article

Gems, D, Virk, RS & de Magalh茫es, JP 2024, '', Ageing Research Reviews, vol. 101, 102546.

de Magalh茫es, JP 2023, '', Genome Biology, vol. 24, no. 1, 51.

Bronikowski, AM, Meisel, RP, Biga, PR, Walters, J, Mank, JE, Larschan, E, Wilkinson, GS, Valenzuela, N, Conard, AM, Magalh茫es, JP, Duan, J, Elias, AE, Gamble, T, Graze, R, Gribble, KE, Kreiling, JA & Riddle, NC 2022, '', Aging Cell, vol. 21, no. 2, e13542.

Short survey

De Magalh茫es, JP & Ocampo, A 2022, '', Trends in Biotechnology, vol. 40, no. 6, pp. 639-642.

De Magalh茫es, JP 2022, '', Trends in Genetics, vol. 38, no. 3, pp. 216-217.