Professor Tarekegn G Hiwot

Photograph of Dr Tarek Hiwot

Department of Metabolism and Systems Science
Honorary Professor

Contact details

Telephone
+44 (0)121 371 6982
Email
t.g.hiwot@bham.ac.uk
Secondary Email
tarekegn.hiwot@uhb.nhs.uk

Career History

  • 2016 - Honorary Reader, Department of Metabolism and Systems Science, UoB
  • 2012 - Honorary Senior Research Fellow, University 麻豆精选
  • 2008 - Consultant in Inherited Metabolic Disorders, UHB NHS FT
  • 2000-7 - Chemical Pathology/Metabolic Medicine (SHO/Registrar), West midlands
  • 1995-2000 - PhD , Molecular Immunology, Karolinska Institute, Sweden
  • 1994-95 - MSc, Biochemistry, Karolinska Institute, Sweden
  • 1990-93 - General practitioners, Addis Ababa, Ethiopia
  • 1989 - MD, Addis Ababa University, Ethiopia

Research

Tarek's group focuses on the deep phenotyping of rare inherited metabolic disorders to provide the best available care for each patient based on stratification into disease subclasses with a common biological basis. They utilise metabolomics, exome sequencing, novel biomarkers and international patient registries to understand the heterogeneity of diseases caused by single gene defect. Their main disease research area of interests are; Niemann-Pick, Fabry, Gaucher, Mucopolysaccharidosis, Alstrom syndrome and Phenylketonuria. 

Group members  

  • Clinical Fellow: Shanat Baig      
  • PhD Students: Fahad Al-Harbi 
  • Research Nurse: Vishy Veeranna   
  • Research coordinator: Shaun Bolton 

Major external collaborators

  • Jeremy Tomlinson (Oxford)
  • Paul Gissen (UCL)
  • Bruno Bembi (University of Udine, Italy)
  • Sandra Sirrs (Vancouver, Canada)
  • Derralynn Hughes (UCL)

Publications

Gathercole LL, Hazlehurst JM, Armstrong MJ, Crowley R, Boocock S, O'Reilly MW, Round M, Brown R, Bolton S, Cramb R, Newsome PN, Semple RK, Paisey R, Tomlinson JW, Geberhiwot T.  Liver Int. 2016 Nov;36(11):1704-1712. doi: 10.1111/liv.13163.

Alharbi FJ, Geberhiwot T, Hughes DA, Ward DG. J Am Soc Mass Spectrom. 2016 Apr;27(4):719-25. doi: 10.1007/s13361-015-1318-4.

  Van Groenendael S, Giacovazzi L, Davison F, Holtkemper O, Huang Z, Wang Q, Parkinson K, Barrett T, Geberhiwot T.  Orphanet J Rare Dis. 2015 Nov 24;10:149. doi: 10.1186/s13023-015-0366-y.

  Edwards NC, Moody WE, Yuan M, Warfield AT, Cramb R, Paisey RB, Geberhiwot T, Steeds RP.  Orphanet J Rare Dis. 2015 Jun 24;10:83. doi: 10.1186/s13023-015-0292-z.

  Paisey RB, Smith J, Carey C, Barrett T, Campbell F, Maffei P, Marshall JD, Paisey C, Steeds RP, Edwards NC, Bunce S, Geberhiwot T.  J Clin Endocrinol Metab. 2015 Aug;100(8):E1116-24. doi: 10.1210/jc.2015-1577.