Professor David J. Hodson BVSc (Hons) PhD FRCVS

David Hodson

Department of Metabolism and Systems Science
Honorary Senior Research Fellow

Contact details

Email
d.hodson@bham.ac.uk
Twitter
Address
Institute of Biomedical Research
University 麻豆精选
Edgbaston
Birmingham
B15 2TT
UK

David is an Honorary Senior Research Fellow and ERC Starting Grant holder.  He has particular interest in using multidisciplinary and innovative approaches (e.g. biophotonics, mouse genetics, modelling, chemical biology) to tackle challenging research questions in metabolism. The overall objective of his work is to identify new mechanisms through which pancreatic alpha-, beta- and delta-cells fail during type 1 diabetes and type 2 diabetes. Further details can be found at

Qualifications

  • Fellow of the Royal College of Veterinary Surgeons (FRCVS), London, 2018
  • Doctor of Philosophy (PhD), University of Bristol, 2008
  • Bachelor of Veterinary Science with Honours (BVSc Hons), University of Bristol, 2005

Biography

David Hodson - Next generation tools to understand endocrine function in health and disease
Dr David Hodson: Diabetes research breakthrough
Being a Birmingham Fellow

David Hodson completed a degree in Veterinary Science before undertaking doctoral studies in reproductive physiology and circadian biology at the University of Bristol with Dr Domingo Tortonese. Subsequently, in 2008, he moved to the laboratory of Dr. Patrice Mollard at the Institut de Genomique Fonctionnelle in Montpellier France (CNRS), where, supported by a Fellowship from the Fondation de la Recherche Medicale (FRM), he pursued postdoctoral studies focused on understanding how endocrine cells residing within the mammalian pituitary gland function as three-dimensional networks to generate hormone release. Following award of a Diabetes UK RD Lawrence Fellowship in 2012, David moved to the Department of Medicine at Imperial College London, where he set up a research group devoted to understanding islet cell heterogeneity in health and disease. In 2016, David moved to the nascent Institute of Metabolism and Systems Research (IMSR) at the University 麻豆精选 where he led the Islet Biology Group.

Teaching

  • Medicine and Surgery MBChB
  • Molecular Medicine
  • Musculoskeletal Ageing and Health

Postgraduate supervision

Currently supervisor to two PhD students and two MSc students.

Research

Research in the Islet Biology Lab tackles challenging questions concerning the regulation of hormone release from pancreatic islets in health and disease. The major aims of the group are to develop novel tools and imaging approaches to understand how alpha, beta and delta cells, which reside within the islet, release hormone to maintain normal glucose. Importantly, we use tissue from individuals with type 1 and type 2 diabetes, as well as animal models, to understand what goes wrong in relevant pathologies. The group is highly inter-disciplinary, and with colleagues in Europe and North America, we combine chemistry, biology and genetics to open up new avenues of exploration in islet biology.

Other activities

  • Senior Birmingham Fellow, University 麻豆精选, 2016-2018
  • Non-Clinical Lecturer in Cell Biology, Imperial College London, 2012-2016
  • FRM Postdoctoral Fellow, CNRS Montpellier, 2010-2012
  • ANR Postdoctoral Fellow, CNRS Montpellier, 2008-2012
  • Locum Veterinary Surgeon, Bristol, 2005-2008

Publications

Recent publications

Article

El-awaisi, J, Kavanagh, D, Heising, S, Maria Schiessl, I, Cleary, S, Hodson, D & Kalia, N 2025, '', Basic research in cardiology.

Cuozzo, F, Viloria, K, Shilleh, AH, Nasteska, D, Frazer-Morris, C, Tong, J, Jiao, Z, Boufersaoui, A, Marzullo, B, Rosoff, DB, Smith, HR, Bonner, C, Kerr-Conte, J, Pattou, F, Nano, R, Piemonti, L, Johnson, PRV, Spiers, R, Roberts, J, Lavery, GG, Clark, A, Ceresa, CDL, Ray, DW, Hodson, L, Davies, AP, Rutter, GA, Oshima, M, Scharfmann, R, Merrins, MJ, Akerman, I, Tennant, DA, Ludwig, C & Hodson, DJ 2024, '', Cell Reports, vol. 43, no. 4, 114047.

Xu, W, Qadir, MMF, Nasteska, D, Mota de Sa, P, Gorvin, CM, Blandino-Rosano, M, Evans, CR, Ho, T, Potapenko, E, Veluthakal, R, Ashford, FB, Bitsi, S, Fan, J, Bhondeley, M, Song, K, Sure, VN, Sakamuri, SSVP, Schiffer, L, Beatty, W, Wyatt, R, Frigo, DE, Liu, X, Katakam, PV, Arlt, W, Buck, J, Levin, LR, Hu, T, Kolls, J, Burant, CF, Tomas, A, Merrins, MJ, Thurmond, DC, Bernal-Mizrachi, E, Hodson, DJ & Mauvais-Jarvis, F 2023, '', Cell Reports, vol. 42, no. 5, 112529.

R眉ckert, AK, Ast, J, Hasib, A, Nasteska, D, Viloria, K, Broichhagen, J & Hodson, DJ 2023, '', Diabetic Medicine, vol. 40, no. 12, e15220.

Viloria, K, Nasteska, D, Ast, J, Hasib, A, Cuozzo, F, Heising, S, Briant, LJB, Hewison, M & Hodson, DJ 2023, '', Diabetes, vol. 72, no. 2, pp. 275-289.

Pezhman, L, Hopkin, S, Begum, J, Heising, S, Nasteska, D, Wahid, M, Rainger, E, Hodson, D, Iqbal, AJ, Chimen, M & McGettrick, H 2023, '', Clinical & Experimental Immunology.

Ast, J, Nasteska, D, Fine, NHF, Nieves, DJ, Koszegi, Z, Lanoisel茅e, Y, Cuozzo, F, Viloria, K, Bacon, A, Luu, NT, Newsome, PN, Calebiro, D, Owen, DM, Broichhagen, J & Hodson, DJ 2023, '', Nature Communications, vol. 14, no. 1, 301.

Galvis, D, Hodson, DJ & Wedgwood, KCA 2023, '', Frontiers in network physiology, vol. 3, 1170930.

Ast, J, Novak, AN, Podewin, T, Fine, NHF, Jones, B, Tomas, A, Birke, R, Ro脽mann, K, Mathes, B, Eichhorst, J, Lehmann, M, Linnemann, AK, Hodson, DJ & Broichhagen, J 2022, '', JACS Au, vol. 2, no. 4, pp. 1007-1017.

Pauza, AG, Thakka, P, Tasic, T, Felippe, I, Bishop, P, Greenwood, MP, Rysevaite-Kyguoliene, K, Ast, J, Broichhagen, J, Hodson, D, Salgado, HC, Pauza, DH, Japundzic-Zigon, N, Paton, JFR & Murphy, D 2022, '', Circulation, vol. 130, no. 5, pp. 694-707.

Hoang, M, Jentz, E, Janssen, S, Nasteska, D, Cuozzo, F, Hodson, D, Tupling, R, Fong, G-H & Joseph, J 2022, '', Endocrinology, vol. 163, no. 1, bqab226, pp. 1-17.

Karsai, M, Zuellig, RA, Lehmann, R, Cuozzo, F, Nasteska, D, Luca, E, Hantel, C, Hodson, D, Spinas, GA, Rutter, G & Gerber, PA 2022, '', Journal of Endocrinology, vol. 253, no. 1, pp. 1-11.

Westbrook, R, Bridges, E, Roberts, J, Escribano Gonzalez, C, Eales, K, Vettore, L, Walker, P, Vera-Siguenza, E, Rana, H, Cuozzo, F, Eskla, K-L, Vellama, H, Shaaban, A, Nixon, C, Luuk, H, Lavery, G, Hodson, D, Harris, AL & Tennant, D 2022, '', Cell Reports, vol. 38, no. 5, 110320.

Birke, R, Ast, J, Roosen, DA, Lee, J, Ro脽mann, K, Huhn, C, Mathes, B, Lisurek, M, Bushir, D, Sun, H, Jones, B, Lehmann, M, Levitz, J, Haucke, V, Hodson, D & Broichhagen, J 2022, '', Organic and Biomolecular Chemistry, vol. 20, no. 30, pp. 5967-5980.

Allen, SL, Seabright, AP, Quinlan, JI, Dhaliwal, A, Williams, FR, Fine, NHF, Hodson, DJ, Armstrong, MJ, Elsharkaway, AM, Greig, CA, Lai, Y-C, Lord, JM, Lavery, GG & Breen, L 2022, '', Cells, vol. 11, no. 7, 1098.